Two of the nine companies laying off staff serve the West Midlands.
This leads to the prospect of another day of reduced services, with some areas not being served at all.
Industry leaders said the 24-hour strike by members of the Aslef union coincided with another busy football weekend. Another big regional event that draws people from outside the area is the Shrewsbury Flower Show.
Network Rail said there will be no services to or from London Euston and Birmingham New Street stations tomorrow due to industrial action.
Meanwhile, there will be no direct Sunday trains from Shrewsbury to London Euston for the next four weeks. Avanti West Coast has announced that a number of weekend trains will be affected by uncertainty surrounding strikes and driver availability.
While some areas will have limited service, the rail company says there will be no “direct” service from Shrewsbury to London Euston on Sundays from August 14. The situation will be reviewed on September 11th.
The strikes will affect Avanti West Coast, West Midlands Trains, Crosscountry, Arriva Rail London, Greater Anglia including Stansted Express, Great Western, Hull Trains, LNER, London Overground and Southeastern.
Passengers are advised to consider a later departure, on Sunday 14 August. Those affected by the strike who have presale, low transport or anytime tickets can use their ticket either the day before the date on the ticket or up to and including Tuesday , August 16, or can change their tickets to travel on a different date, or receive a refund if their train is canceled or rescheduled.
Steve Montgomery, Chairman of Rail Delivery Group, said: “We are genuinely disappointed that for the second time in as many weeks, Aslef leadership have decided to impose even more uncertainty on passengers and businesses by disrupting passengers’ weekend plans.
“I will reiterate what I have said before – I am ready and willing to speak to Aslef leadership today, tomorrow or even anytime next week. You should cancel the promotion next week and talk to us instead. What our passengers and our employees expect is that we talk about it and find a way.
“While we will do everything we can to minimize disruption and get passengers where they need to be, please plan ahead when traveling on the affected routes and check the latest travel advice.
“As with any service or business, things don’t just stand still and we have to move with the times. We want to give our people a raise because we know everyone feels the hardship of the rising cost of living.
“We have to find the money somewhere because we can’t ask taxpayers or passengers for more, so we have to modernize and adapt to changing passenger behavior.
“By making these necessary reforms, such as For example, ending the weekend volunteering dependency, we improve punctuality, have more resilient Sunday services, and use those savings to give our employees a raise, which is something we’ve always wanted.
“Further strikes will take our people out of pocket and mean less money to fund a pay rise, so we are asking Aslef leadership to come and talk to us so we can reach an agreement that will work for staff fair to taxpayers and a bright, long-term future for our railway.”
Other actions are planned for August 18th and 20th by the RMT union, the Transport Salaried Staffs Association and Unite.